Increased expression of peroxisome proliferator-activated receptors (PPARS) in resistance arteries of spontaneously hypertensive rats
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چکیده
منابع مشابه
Downregulation of peroxisome proliferator-activated receptors (PPARs) in nasal polyposis
BACKGROUND Peroxisome proliferator-activated receptor (PPAR) alpha, betadelta and gamma are nuclear receptors activated by fatty acid metabolites. An anti-inflammatory role for these receptors in airway inflammation has been suggested. METHODS Nasal biopsies were obtained from 10 healthy volunteers and 10 patients with symptomatic allergic rhinitis. Nasal polyps were obtained from 22 patients...
متن کاملPeroxisome Proliferator-Activated Receptors (PPARs): Choreographers of Metabolic Gene Transcription
Nuclear receptors are ligand-activated transcription factors that regulate gene expression in response to small lipophilic compounds such as testosterone [androgen receptor (AR)], oxysterols [liver X receptor (LXR)], estrogen (ER), xenobiotics [pregnane X receptor (PXR)], retinoic acid (RAR), thyroid hormone (TR), bile acids [farnesoid X receptor (FXR)] and vitamin D (VDR). The peroxisome proli...
متن کاملIncreased expression of peroxisome proliferator-activated receptor-alpha and -gamma in blood vessels of spontaneously hypertensive rats.
Peroxisome proliferator-activated receptors (PPARs) are a family of ligand-activated transcription factors that include PPAR-alpha, PPAR-gamma, and PPAR-delta. We hypothesized that PPAR expression in blood vessels could be reduced in hypertension to result in increased vascular growth and reduced apoptosis. We investigated the abundance of PPAR-alpha and PPAR-gamma in aorta and mesenteric arter...
متن کاملIncreased Expression of Peroxisome Proliferator-Activated Receptor-a and -g in Blood Vessels of Spontaneously Hypertensive Rats
Peroxisome proliferator-activated receptors (PPARs) are a family of ligand-activated transcription factors that include PPAR-a, PPAR-g, and PPAR-d. We hypothesized that PPAR expression in blood vessels could be reduced in hypertension to result in increased vascular growth and reduced apoptosis. We investigated the abundance of PPAR-a and PPAR-g in aorta and mesenteric arteries from young (6-we...
متن کاملExpression of the Peroxisome Proliferator-Activated Receptors (PPARs) in the Hepatic Stellate Cells
Email: Takeya Sato* [email protected]; Mitsuru Sato [email protected]; Mitsutaka Miura [email protected]; Nobuyo Higashi [email protected]; Da-Ren Wang [email protected]; Shinsuke Suzuki [email protected]; Katsuyuki Imai [email protected]; Naosuke Kojima [email protected]; Haruki Senoo [email protected] * Corresponding author
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ژورنال
عنوان ژورنال: American Journal of Hypertension
سال: 2001
ISSN: 0895-7061
DOI: 10.1016/s0895-7061(01)01318-8